The Department of Infectious Diseases came into being in the early 1990’s under the leadership of Professor Vinod Gathiram. The impetus for the creation of the department was the need for academic leadership to address the emerging HIV/AIDS epidemic. Professor Vinod Gathiram’s untimely death was a major blow to the development of the specialty at University of KwaZulu Natal. The then head of the Department of Medicine, Professor Umesh Lalloo, managed the Department of Infectious Diseases until the post of Chief Specialist was filled in 2004. Currently, the unit consists of 2 full-time Consultants, one honorary lecturer, one medical officer and a Registrar in rotation from the General Medicine pool. All clinical services are currently undertaken at King Edward VIII Hospital.