• An international multicentre prospective observational study of the immunopathogenesis of immune
restoration Disease in severely immunodeficient HIV patients commencing antiretroviral therapy
(MIRSAT).“ The focus at the Durban site is identify patients with cryptococcal meningitis who deteriorate
following antiretroviral treatment with a view studying various immunological parameters which is
expected to contribute to the understanding of the immunopathogenesis of this syndrome. This study will
form the basis for a PhD for a student from Monash University, Australia who is being hosted in the
Department of Infectious Diseases.
sample obtained by enteric capsular device with induced sputum.
reconstitution inflammatory syndrome (IRIS).